Sildenafil should be used with caution in patients with a predisposition to priapism (for example, with sickle cell anemia, multiple myeloma or leukemia) or in patients with anatomical deformity of the penis (for example, with angulation, cavernous fibrosis or Peyronie's disease). The patient should be informed about the need for immediate medical attention in case of an erection lasting 4 hours or more. Untimely treatment of priapism leads to damage to the tissues of the penis, resulting in a long-term loss of potency.
Problems in the intimate sphere can deprive a man of peace and sleep, significantly lower his self-esteem and lead to depression. And do not think that such problems arise only in men over 50 and older. Erectile dysfunction has become significantly younger, and you can often hear about 30-year-old young men suffering from sexual disorders.The modern market of medical products is ready to offer its patients a large list of tools that will help to induce a high-quality erection over a fairly long period. One of these tools is Cialis. In pharmacies, it can be purchased both individually (1 tablet each) and in packages with a wide variety of quantities (5, 10, 20, 30, 40, 50, 100 pieces).
Viagra belongs to a group of medications designed to improve erectile function. The main active ingredient of the drug is tadalafil. Lactose monohydrate, hyprolase, sodium lauryl sulfate, sodium croscarmellose and vegetable magnesium stearate act as auxiliary. Tablets are available in oval shape in a light yellow film shell. On one side of the tablet, you can see the engraving C5.
The drug Viagra action is based on the fact that tadalafil - the main active ingredient - suppresses specific PDE-5 (phosphodiexterase). During the onset of sexual arousal, nitric oxide is released in a sufficiently large amount, which leads to an increase in the concentration of cGMP in the cavernous body of the penis (the action is similar to cAMP in the human body, it plays the role of a secondary mediator, the purpose of which is the intracellular distribution of signals of certain hormones that are not able to overcome the cell membrane).